Effect of anti-depression drug on patients with unstable angina pectoris combined with depression

Objective: To observe the curative effect of anti-depression drug in treatment of patients with unstable angina pectoris accompanied by depression.Methods: Fifty-eight patients were randomly divided into two groups.In addition to the routine therapy,the treatment group were administered paroxetine 20-60 mg a day or xitaipulan 10-40 mg a day orally.Both groups were observed for eight weeks.Results: The symptom of depression in the treatment group was improved and the angina pectoris released(P<0.05),but no obvious effect was observed in the electrocardiogram of patients with unstable angina pectoris(P>0.05).Conclusions: Anti-depression drug may effectively relieve the symptom of depression and the angina pectoris,and improve the life quality of patients with unstable angina pectoris.