Effect of atorvastatin on pulse pressure in patients with essential hypertension

Objective: To evaluate the effect of atorvastatin on pulse pressure in patients with essential hypertension(EH) . Methods: One hundred and eight EH patients were randomly allocated into two groups:common treated group(54 cases) and atorvastatin treated group(54 cases) . Patients in common treated group were accepted common treatment and those in atorvastatin treated group were treated with atorvastatin 40 mg daily besides common treatment. All of them were treated for 12 weeks. Pulse pressure was compared between the two groups before treatment and after 4, 8 , 12 weeks treatment. Results: There was no difference of pulse pressure between two groups before treatment(P ＞ 0. 05) , but was significantly lower in atorvastatin treated group than in common treated group after treatment(P ＜ 0. 01) , and with the treatment prolonging, pulse pressure had an obvious lower tendency in atorvastatin treated group(P ＜ 0. 01) . Conclusions: Atorvastatin could decrease pulse pressure effectively in patients with EH.