The application value of MoCA and MMSE in the early diagnosis of subcortical ischemic vascular disease

Objective: To compare the diagnostic value of MoCA and MMSE in subcortical ischemic vascular disease( SIVD). Methods: In 98 cases with vascular cognitive impairment( vMCI),50 cases( MoCA-M group) and 48 cases( MMSE-M group) were measuured by MoCA and MMSE,respectively. In 85 control cases,46 cases( MoCA-C group) and 39 cases( MMSE-C group) were measured by MoCA and MMSE,respectively. Results: The sensitivity of MoCA-M group( 78. 0%) in patients with vMCI was significantly higher than that of MMSE-M group( 52. 1%)( P 0. 01). The specificity of MoCA-M group( 71. 7%) in patients with vMCI was higher than that of MMSE-M group( 48. 7%)( P 0. 05). Conclusions: MoCA has high sensitivity and specificity for detecting vMCI,which may become a effective way for the early diagnosis of SIVD in clinic.