The literature analysis of Kimura disease

Objective: To review the clinical features of Kimura disease and investigate its diagnosis， therapy and prognosis. Methods:The clinical manifestation， laboraObjective: Tory examination， therapy and prognosis of 49 patients with Kimura disease searched by Wanfang database from 2001 Objective: To 2011 were analyzed. Results: Head and neck neoplasm，swelling lymph nodes and large salivary gland involvement complicating with nephrotic syndrome were the clinical features of the Kimura disease. The increasing peripheral osinophil count， the rising serum IgE level and the negative double-stranded DNA were found. The lesion boundary was not clear and no envelope. The glucocorticoid therapy was effective，but easy Objective: To relapse. Two patients transformed inObjective: To malignant lymphoma.Conclusions: The cause of Kimura disease is unknown. It is a chronic inflammaObjective: Tory disease complicated with kidney chronic inflammation. The peripheral lymph nodes and large salivary glands are often involved. The glucocorticoid therapy is effective，but easy Objective: To relapse. Kimura disease has the tendency of transforming inObjective: To malignant lymphoma.