Comparison of anesthesia induction with fentanyl and remifentanil on agitation during anesthesia recovery period in laparoscopic cholecystectomy patients

Objective:To compare the anesthesia induction with fentanyl and remifentanil on agitation during anesthesia recovery period in laparoscopic cholecystectomy patients． Methods:ASAⅠ or Ⅱ laparoscopic cholecystectomy patients were randomly divided into remifentanil group(R group) and fentanyl group(F group)，to observe restlessness score． Inducing drugs:R group remifentanil 1 g/kg，midazolam 3 mg，propofol 2 mg/kg，rocuronium 0． 6 mg/kg;F group were fentanyl 3． 0 g/kg replace remifentanil，others medication with agree R group accord． To maintain anaesthesia by micro pump constant velocity input remifentanil 0． 2 gkg－1 min－1propfol 2 mgkg－1h－1and inhaling 1% － 2% sevoflurane． Compare agitation score in two groups before extubation， extubation，10 min after extubation． Results:Restlessness score in R group were higher than those in F group before extubation， extubation，10 min after extubation(P 0． 01)． Differences of two groups of patients with spontaneous breathing recover time，awake time were not significant(P ＞0． 05)． Conclusions:Anesthesia induction with fentanyl can effectively reduce agitation during anesthesia recovery period in laparoscopic cholecystectomy patients．