Clinical analysis for 128 patients with multiple primary carcinomas

Objective: To analyze the incidence of multiple primary carcinomas.Methods: Records of 128 patients with multiple primary carcinomas during ten years period between July 1993 and June 2003 were reviewed.Results: One hundred and twenty-eight patients with multiple primary carcinomas were observed.Among them,113 patients had double primary carcinomas,12 had triple primary carcinomas,and 3 had quadruple primary carcinomas.The ratio of male to female was 2.28∶1.The average age was 58.4 years old.There were 41 synchronous carcinomas and 87 metachronous ones.The cancers in decreasing sequence were head and neck region > digestive > breast > lung.Conclusions: The possibility of multiple primary carcinomas should be emphasized,especially in head and neck cancer patients and digestive cancer patients.When diagnosis is definite,the radical therapy should be performed.