Low molecular weight heparin in treatment of transient ischemic attack

Objective: To study the effect of low molecular weight heparin(LMWH) in treatment of transient ischemic attack(TIA).Methods: Fifty-four patients were randomly divided treatment group and control group.The treatment group were injected LMWH 5000IU once every 12 hours for 10 days,while the control group were given asprine 150 mg orally once a day.The times of attack and the changes of fibrinogen(FIB),prothrombin time(PT) and activated partial thromboplastin time(APTT) were observed.Results: The effective rates were 88.9% and 66.7% in the treatment group and the control group respectively.The difference was significant.There were no significant differences between FIB,PT and APTT(P>0.05),before and after treatment.No hemorrhage or other complications occurred.Conclusions: LMWH is effective and safe for treatment of TIA.