Relationship between platelet parameters on acute hypersensitive purpuric nephritis and kidney damage in children

Objective: To discuss the correlation between platelet parameters on acute hypersensitive purpura and kidney damage in children.Methods: Blood corpuscle analyser was used to test the blood platelet count(BPC),mean platelet volume(MPV),plateletcrit(PCT) and platelet distribution width(PDW) of 51 children suffering from hypersensitive purpura.Results: The values of PLT and MPV were obviously higher in the group with kidney damage than those in the group without kidney damage BPC during the acute period(P<0.01).Conclusions: Platelet is involved in the process of kidney lesion induced by hypersensitive purpura,so conjoint treatment with anti-platelet and anti coagulation may prevent or alleviate kidney lesion.