The establishment of four biological reference intervals of blood coagulation of adults in Lu'an city

Objective: To detect the levels of prothrombin time(PT),the activated partial thromboplastin time(APTT),plasma fibrinogen(FIB) and thrombin time(TT) of healthy adults in Lu'an city,and establish the biological intervals.Methods: The levels of PT,APTT,FIB and TT in 300 healthy adults were detected by Cluass method using automated blood coagulation analyzer STA-compact.Results: The biological reference intervals of PT,APTT,FIB and TT of healthy adults in Lu'an city were 11.06 to 14.24 s,27.57 to 42.23 s,1.91 to 3.99 g/L and 14.05 to 18.47 s,respectively.Conclusions: The biological reference intervals have important signficances in early prevention and diagnosis,therapeutic effect and prognosis of disease.Each clinical laboratory should formulate the reference intervals.