Relationship between mortality and blood pressure admission in patients with acute stroke

Objective: To evaluate the relationship between systolic blood pressure(SBP) or diastolic blood pressure(DBP) on admission and early mortality in patients with acute stroke.Methods: A total of 461 patients admitted within 24 h from stroke onset and followed up for 1 month.Mortality at 1 month after stroke in relation to admission SBP and DBP.Results: Early mortality in patients with acute ischaemic or haemorrhagic stroke in relation to admission SBP and DBP followed a U-curve pattern.The nadir or U-point of the curve occurred in the range of 121-140/81-90 mmHg and 141-160/91-100 mmHg for ischaemic or haemorrhagic stroke patients.The patients with high and low admission BP-values have a higher early mortality(P<0.05~P<0.01).Death due to cerebral oedema was significantly more frequent in patients with high admission SBP-values,whereas death due to cardiovascular disease was more frequent in patients with low admission SBP-values.Conclusions: Acute ischaemic or haemorrhagic stroke patients with high and low admission BP-values have a higher early mortality.Coincidence of heart disease is associated with low initial BP-values.Death due to neurological damage from brain oedema is associated with high initial BP-values.