Umbilical artery flow velocity examination and nonstretss test for predicting perinatal prognosis in patients with intrahepatic cholestasis in pregnancy

Objective: To study the value of umbilical artery flow velocity and nonstress test(NST) for patients with intrahepatic cholestasis in pregnancy(ICP).Methods: Fetal umbilical artery Doppler velocity and NST were used in 71 patients with ICP and 60 healthy women.Results: The incidence of S/D and abnormal NST was higher in the ICP group than that in the control group(P<0.05).The incidence of poor perinatal outcome in patients with abnormal S/D and NST was significantly higher than that of the control(P<0.005).Conclusions: Patients with ICP should receive examination of fetal umbilical artery blood flow and NST regularly in order to improve the perinatal prognosis.