HUANG Han-sheng, YANG Lan-ping. Clinical observation of 29 cases on the effect of gemcitabine and cisplatin for treatment of advanced soft tissue sarcoma[J]. Journal of Bengbu Medical University, 2011, 36(9): 968-970.
    Citation: HUANG Han-sheng, YANG Lan-ping. Clinical observation of 29 cases on the effect of gemcitabine and cisplatin for treatment of advanced soft tissue sarcoma[J]. Journal of Bengbu Medical University, 2011, 36(9): 968-970.

    Clinical observation of 29 cases on the effect of gemcitabine and cisplatin for treatment of advanced soft tissue sarcoma

    • Objective: To analyze the clinical efficacy of gemcitabine and cisplatin for treatment of advanced soft tissue sarcoma. Methods: Twenty-nine patients with soft tissue sarcoma hospitalized were treated with gemcitabine and cisplatin chemotherapy:gemcitabine 1 000 mg/m2 intravenous infusion, d1,8; cisplatin 30 mg/m2 intravenous infusion, d1-3. The efficacy and toxicity were observed. Results: One case was achieved complete response,14 cases were partial response,7 cases with stable disease and 7 cases with progressed disease. The total response rate was 75.86%. The main side effects were myelosuppression and gastrointestinal reactions,no significant liver and kidney damage. Conclusions: Gemcitabine and cisplatin chemotherapy in the treatment of advanced soft tissue sarcoma has the good effect,and well tolerated.
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