Efficacy of azithromycin in the treatment of mycoplasmal pneumonia：a report of 25 cases

Objective: To investigate the clinical efficacy of azithromycin in the treatment of mycoplasmal pneumonia.Methods: Fifty children with mycoplasmal pneumonia were randomly divided into two groups.The 25 cases in the control group received the therapy of erythromycin 30 mg/kg,1 time/day,continuously for 5 days and a 2-day withdrawal as one course,and the 25 cases in the observation group azithromycin 10 mg/kg,1 time/day,continuously for 5 days and a 2-day withdrawal as one course.The clinical efficacy and changes of pulmonary ventilation function were compared between the two groups.Results: The total response rate of the observation group was 96.0%,which was higher than that of the control(76.0%)(P<0.05).The time of cough disappearing,rales disappearing and hospital stay of the observation group was shorter than that of the control group(P<0.01);the Forced vital capacity and Forced expiratory volume in 1 second of the observation group were higher than those of the control group after 2 months' treatment(P<0.01);the gastrointestinal reaction of the observation group was less than that of the control group(P<0.05).Conclusions: The clinical efficacy of azithromycin is confirmed for treatment of mycoplasmal pneumonia.It may shorten the duration of the clinical symptoms and signs,decrease the treatment time and hospital stay,reduce the adverse reaction and improve the lung function.