Relationship between carotid atherosclerosis,high-sensitive C-reactive protein and fibrinogen in coronary heart disease

Objective: To investigate the correlation of carotid atherosclerosis(CAS),high-sensitive C-reactive protein(hs-CRP) and fibrinogen(FIB) in patients with coronary heart disease(CHD).Methods: Seventy-eight patients who had received coronery artery angiography(CAG) examination were included in this study.According to the results of CAG,the patients were divided into single vessel group and multiple vessel groups.The intima media thickness(IMT) and plague of each patient was measured by ultrasound.The levels of hs-CRP and FIB were measured and compared.Results: The levels of IMT,plagues,hs-CRP and FIB in CHD group were higher than those in negative group(P<0.05 to P<0.01).CAS,hs-CRP and FIB were positively correlated with the count of coronary atheroscleroic lesions(P<0.05 to P<0.01).Conclusions: Carotid ultrasounic examination could help to predict the presence of coronary artery disease.The levels of hs-CRP and FIB play an important role in the initiation and progression of CHD.The IMT,hs-CRP and FIB have positive correlation with the count of coronary atheroscleroic lesions.