Analysis of insulin resistance related factors among hypertensive population

Objective: To explore the insulin resistance related factors among hypertensive population.Methods: Two hundred and three hypertensive patients in community were included in this study;The medical history,physical examination data,the levels of fasting plasma glucose,fasting insulin(FIN),triglyceride(TG) and high density lipoprotein cholesterol of the patients were tested;setting the background population of 1/4 point(3.71) as the cutting point,the effect of different factors on insulin resistance index(HOMA-IR) was analyzed after the HOMA-IR was calculated.Results: The family history of hypertension and the course of disease had no correlation to HOMA-IR(P>0.05),but the age of patients had negatively correlation to HOMA-IR(P<0.01).Among the metabolism factors,obesity,high TG and glucose have positive correlation to HOMA-IR(P<0.05).About the life styles,the intakes of animal foodstuff and low amounts of exercise have positive correlation to HOMA-IR(P<0.05).In the regression analysis,BMI,age and systolic pressure were the influence factors,when the FIN was set as the independent variable.Conclusions: Among the hypertensive population,different risk factors had different impacts on IR.Significant insulin resistance was usually related to individuals with bad life styles and metabolic syndrome. More