Clinical significance of changes of serum level of C-reactive protein in patients with acute cerebral infarction

Objective: To investigate the changes of the serum level of C-reactive protein(CRP) in patients with acute cerebral infarction and its relationship to the severity of cerebral infarction.Methods: The serum level of CRP in 63 patients and 24 healthy persons was determined.All the patients were scored by clinic neurological deficit scale(NDS),and compared in groups.Results: The serum level of CRP in the patients was significantly higher than that in normal controls(P<0.01) and it was significantly higher in the serious group than in the middle and mild groups(P<0.01).Conclusions: The serum level of CRP is closely correlated with the severity of cerebral infarction.