The expression and significance of interleukin-6 in epithelial ovarian carcinoma

PENG Cheng; LI Min; ZHOU Ying; ZHAO Wei-dong; FENG Ding-qing; LING Bin

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Journal of Bengbu Medical University > 2009 > 34(2): 117-119.

PENG Cheng, LI Min, ZHOU Ying, ZHAO Wei-dong, FENG Ding-qing, LING Bin. The expression and significance of interleukin-6 in epithelial ovarian carcinoma[J]. Journal of Bengbu Medical University, 2009, 34(2): 117-119.

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The expression and significance of interleukin-6 in epithelial ovarian carcinoma

1. Department of Obstetrics and Gynecology, Anhui Provincial Hospital Affiliated of Anhui Medical University, Hefei Anhui 230001;
2. Anhui Province Key Laboratory of Molecular Medicine, Hefei Anhui 230001, China

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Received Date: August 12, 2008

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Objective: To explore the expression and significance of interleukin-6 in epithelial ovarian carcinoma.Methods: Twenty epithelial ovarian carcinomas and ten normal ovarian tissues were examined by Western blot and RT-PCR in the protein and mRNA level.Results: The expression of IL-6 in epithelial ovarian carcinoma was obviously lower than that in normal ovarian tissue,both in protein and mRNA level,the difference had statistic significance(P=0.000).Conclusions: The low expression of interleukin-6 in epithelial ovarian carcinoma provides the experimental evidence for the further study on the the effect of interleukin-6 on the development of ovarian cancer.
- epithelial ovarian carcinoma,
- interleukin-6,
- signal transducers and activators of transcription 3

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The expression and significance of interleukin-6 in epithelial ovarian carcinoma

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