Detection of circulating immune complex in diagnosis of neurocysticercosis

Objective: To explore the value of detecting the circulating immune complex in diagnosis of neurocysticercosis.Methods: A double mono-clonal antibody sandwich enzyme-linked immunosorbent assay(ELISA)was used to detect the circulating antigens,antibodies and immune complex in 109 sera of neurocysticercosis.Results: In the 109 cases of neurocysticercosis,the positive rates of circulating antigens,antibodies and immune complex were 33.03%,68.81% and 47.71%,respectively.Twelve of the 52 cases with positive immune complex showed negative when tested for the antigens and antibodies separatedly.Conclusions: Detection of the specific immune complex may help to the diagnosis of neurocysticercosis.