Change of serum interleukin-6 in patients with acute cerebral infarction and its significance

Objective: To investigate the relations between the serum level of interleukin-6(IL-6) and the severity of acute cerebral infarction.Methods: The serum level of IL-6 in 63 patients with acute cerebral infarction and 24 healthy persons was determined.All the patients were scored by clinic neurological function deficit scale(NDS),and comparision was made between the groups.Results: The serum level of IL-6 of the patients was significantly higher than that of the normal control(P<0.01),and the serum level of IL-6 of the group with serious cerebral infarction was significantly higher than the groups with middle and mild cerebral infarction(P<0.01).Conclusions: The serum level of IL-6 is closely correlated with the severity of cerebral infarction.